Knowledgebase

COSMIC's Knowledgebase contains expertly curated somatic mutation data in cancer

COSMIC product

Explore COSMIC's product and the breadth of cancer types and sources it contains.

COSMIC is the world’s most comprehensive and respected Knowledgebase for somatic mutations in human cancers. We provide users with clinically and biologically curated data and relevant genomic insights, to empower discoveries.

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COSMIC modules

With over two decades of experience in an exceptional scientific ecosystem, we excel in standardising genomic data into a unified, trusted resource. 

Consisting of the Core COSMIC data and six associated modules, our expertly curated somatic mutation Knowledgebase enables researchers and clinicians to unveil trusted findings and ultimately further scientific discovery.

This photo shows screenshots of COSMIC (Catalogue of Somatic Mutations In Cancer) knowledgebase with data image visualisation both on computer screens.

COSMIC curation

Explore how COSMIC delivers expertly curated, high-quality data you can trust. 

Our expert Scientific Curators ensure accuracy through rigorous quality control, filtering out unreliable data while collaborating with authors to resolve inconsistencies. 

Discover the curation process that empowers researchers, clinicians, and drug developers with actionable insights to drive discoveries and refine clinical decision-making.

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How to access COSMIC data

COSMIC's web platform provides a dynamic, graphical interface to explore mutations in their full genomic context. Every data point is hyperlinked, allowing users to trace mutations back to their original sources of publication, essential for complex case investigations.

For use in larger scale analysis, entire or specific datasets can be seamlessly downloaded for integration into data warehouses, NGS pipelines, or other data analysis workflows.

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